Just a mention that TTS engine Piper (easy install via GitHub - Elleo/pied: Pied makes it simple to install and manage text-to-speech Piper voices for use with Speech Dispatcher.) works reasonably well on GNOME with its built-in screen reader (orca)
UPD: there's an upstream bug tho Keyboard when Screen Reader is enabled on Ubuntu 20.04 · Issue #24506 · electron/electron · GitHub
tags for search
Text to speech, Linux, Ubuntu, Fedora, blind, read aloud, reading out loud, speech-dispatcher, Accessibility, Voice Synthesis