Thanks former_evernotist. I tend to lose USB drives, but if I can install it within a VeraCrypt container on an internal SSD, that's a possibility. I'd prefer to be able to swap the profiles within one instance of Joplin once the encrypted profile is mounted (if that's even possible) but your method is certainly a fall back option. Can you sync to cloud storage with end to end encryption as normal from withiin a mounted container?